Dementia isn’t prevented with a late-life drug. It’s shaped in midlife—through sleep, metabolism, nervous system state, hormones, and vascular resilience. Midlife isn’t the problem. It’s the intervention window.
When old infections resurface in menopause, it’s rarely new exposure. Hormonal withdrawal shifts immune surveillance, triggering a terrain audit that revisits what was once contained.
Menopause immune changes are feedback. As estrogen withdraws, immune tolerance gives way to audit, reveals congestion, mis-timing, and unresolved terrain.
When estrogen withdraws, the gut loses more than hormones—it loses tone, timing, and diplomatic balance. Menopause gut symptoms reveal how the nervous and immune systems renegotiate leadership.
